Anatomy, three-dimensional reconstructions, and volume estimation of the brain of the Atlantic White-sided Dolphin (Lagenorhynchus acutus) from magnetic resonance images
Title | Anatomy, three-dimensional reconstructions, and volume estimation of the brain of the Atlantic White-sided Dolphin (Lagenorhynchus acutus) from magnetic resonance images |
Publication Type | Conference Paper |
Year of Publication | 2004 |
Authors | Montie, E. W., M. Moore, D. R. Ketten, J. J. Arruda, S. R. Cramer, I. Fischer, K. E. Touhey, K. Patchett, A. Bogomolni, B. Lentell, B. Sharp, G. Early, and M. Hahn |
Conference Name | New England Stranding Conference |
Keywords | 3d anatomy, atlantic white-sided dolphin, brain, brain volume, dolphin, lagenorhynchus acutus, magnetic resonance imaging, marine mammals, MRI, odontocetes |
Abstract | Thyroid hormones (TH) play an integral role in neuro-development, particularly in the maturation of the corpus callosum, cerebellum, hippocampus, and inner ear. In rodents, it has been shown that persistent organic pollutants (POPs), particularly polychlorinated biphenyls (PCBs), interfere with TH signaling. These pollutants are widespread in the marine environment and biomagnify in marine mammals to very high levels. Brominated flame-retardants have also recently been shown to interfere with the TH system in experimental animals. Although at the present time levels are much lower than PCBs, flame-retardants have been shown to biomagnify in marine mammals. Hence, there is concern that PCBs and flame-retardants with similar mechanisms of toxicity may affect neuro-development of marine mammals. |
Full Text | Thyroid hormones (TH) play an integral role in neuro-development, particularly in the maturation of the corpus callosum, cerebellum, hippocampus, and inner ear. In rodents, it has been shown that persistent organic pollutants (POPs), particularly polychlorinated biphenyls (PCBs), interfere with TH signaling. These pollutants are widespread in the marine environment and biomagnify in marine mammals to very high levels. Brominated flame-retardants have also recently been shown to interfere with the TH system in experimental animals. Although at the present time levels are much lower than PCBs, flame-retardants have been shown to biomagnify in marine mammals. Hence, there is concern that PCBs and flame-retardants with similar mechanisms of toxicity may affect neuro-development of marine mammals. |
- anatomy
- Atlantic
- atlantic white sided dolphin
- Atlantic white-sided dolphin
- beluga whale
- biomagnify
- bottlenose dolphin
- brain
- brain chemical
- brain hippocampus
- brain size
- brain volume
- central nervous system
- cerebellum
- cerebral cortex
- chemical data
- common dolphin
- dolphin
- Environment
- estimation
- Flame retardants
- Harbour Porpoise
- hippocampus
- Imaging
- internal brain
- Lagenorhynchus acutus
- magnetic resonance images
- magnetic resonance imaging
- marine mammals
- MRI
- necropsy procedure
- neuroanatomy
- Neurology
- odontocetes
- Persistent organic pollutants
- Polychlorinated biphenyl
- resonance
- thyroid
- thyroid hormone
- thyroid hormone disrupting chemicals
- thyroid hormones
- volume
- volume estimation
- white sided dolphin